Main Scientific Publications | Biomarker | ECS progastrin

ECS progastrin SA is a subsidiary of

Progastrine Invest SCSp – Cancer Control Funding Fund

11 côte d'Eich, L1450,

Luxembourg City - Grand Duchy of Luxembourg

Progastrine invest

11 côte d'Eich,

L1450 Luxembourg ville

Grand Duché du Luxembourg

ECS progastrin Lab

Chemin de la Meunière 12

Prilly 1008

Suisse

Progastrin Manufacturing

Chemin de la Meunière 12

Prilly 1008

Suisse

Progastrine et cancers

11 côte d'Eich,

L1450 Luxembourg ville

Grand Duché du Luxembourg

Eurobiodev

2040 avenue du Père Soulas

34000 Montpellier

France

Progastrine Invest SCSp and its subsidiaries

  • focus on innovation in cancer screening, diagnosis and treatment,

  • hold the rights to the first circulating progastrin assay, identified as a new marker associated with cancer. This dosage helps to screen for cancer even at early stages and to monitor therapies,

  • are the holders of the rights to the cancer therapy project with an anti-progastrin antibody.

 

For ethical reasons and out of respect for practitioners, health institutions, populations and regulations in force in all countries where they operate, Progastrine Invest SCSp and its subsidiaries pay extreme attention to the information they publicly provide.

 

The management of Progastrine Invest SCSp, its subsidiaries and their scientific committee would like to remind you that only information published on the official communication media of the group's companies can be considered as confirmed and authorised.

© 2018 ECS progastrin

 

Main Scientific Publications

Main Scientific Publications

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Gastroenterology, 2017 September Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Anton Gies, PhD student, Katarina Cuk, PhD, Petra Schrotz-King, PhD, Hermann Brenner, MD, MPH Abstract Background & Aims A variety of fecal immunochemical tests (FITs) for hemoglobin (Hb) are used in colorectal cancer (CRC) screening. […]

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Clinical Cancer Research, 2017 June Targeting the Wnt pathway and cancer stem cells with anti-progastrin humanized antibodies: a major breakthrough for K-RAS mutated colorectal cancer treatment Author information Alexandre Prieur, Monica Cappellini, Guillaume Habif, Marie-Paule Lefranc, Thibault Mazard, Eric Morency, Jean-Marc Pascussi, Maud Flaceliere, Nathalie Cahuzac, Berengere Vire, Benjamin Dubuc, Amandine Durochat, Pierre Liaud, Jérémy […]

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Nature reviews, 2017 May Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information William G. Kaelin Jr Abstract An alarming number of papers from laboratories nominating new cancer drug targets contain findings that cannot be reproduced by others or are simply not robust enough to justify drug […]

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JAMA Oncol. 2016 Dec 3. Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Global Burden of Disease Cancer Collaboration, Fitzmaurice C1, Allen C2, Barber RM2, Barregard L3, Bhutta ZA4, Brenner H5, Dicker DJ2, Chimed-Orchir O6, Dandona R7, Dandona L2, Fleming T2, Forouzanfar MH2, Hancock J2, Hay […]

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Cancer Res. 2016 June Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Giraud J1, Failla LM2, Pascussi JM1, Lagerqvist EL1, Ollier J1, Finetti P3, Bertucci F3, Ya C1, Gasmi I1, Bourgaux JF4, Prudhomme M4, Mazard T5, Ait-Arsa I5, Houhou L6, Birnbaum D3, Pélegrin A5, Vincent C5, […]

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Lab Invest. 2016 February Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Yang K1,2,3, Wang X2,4, Zhang H2,5, Wang Z1,2, Nan G1,2, Li Y1,2, Zhang F2,5, Mohammed MK2, Haydon RC2, Luu HH2, Bi Y1,2, He TC1,2,5. Abstract The canonical WNT/β-catenin signaling pathway governs a myriad of […]

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Oncogene. 2015 June Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Najib S1, Kowalski-Chauvel A1, Do C1, Roche S2, Cohen-Jonathan-Moyal E3, Seva C1. Abstract Angiogenesis is essential in tumor progression and metastatic process, and increased angiogenesis has been associated with poor prognosis and relapse of colorectal […]

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J Physiol. 2014 Jul 15 Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Dimaline R1, Varro A2. Abstract The existence of the hormone gastrin in the distal stomach (antrum) has been known for almost 110 years, and the physiological function of this amidated peptide in regulating […]

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Curr Opin Gastroenterol. 2013 Nov Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Chu S1, Schubert ML. Abstract Purpose of review The review summarizes the past year’s literature, basic science and clinical, regarding the neural, paracrine, hormonal, and intracellular regulation of gastric acid secretion. Recent findings […]

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Cold Spring Harb Perspect Biol. 2012 May Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Paul Polakis Abstract Aberrant regulation of the Wnt signaling pathway is a prevalent theme in cancer biology. From the earliest observation that Wnt overexpression could lead to malignant transformation of mouse […]

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Cancer Res. 2009 August Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Pannequin J1, Bonnans C, Delaunay N, Ryan J, Bourgaux JF, Joubert D, Hollande F. Abstract The Wnt and Notch signaling pathways are both abnormally activated in colorectal cancer (CRC). We recently showed that progastrin […]

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Gastroenterology. 2007 Nov. Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Pannequin J1, Delaunay N, Buchert M, Surrel F, Bourgaux JF, Ryan J, Boireau S, Coelho J, Pélegrin A, Singh P, Shulkes A, Yim M, Baldwin GS, Pignodel C, Lambeau G, Jay P, Joubert D, Hollande […]

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J Clin Invest. 2000 August Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Koh TJ1, Bulitta CJ, Fleming JV, Dockray GJ, Varro A, Wang TC. Abstract Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene occur in most colorectal cancers and lead to activation of […]

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Gastroenterology. 1993 April Direct Comparison of Diagnostic Performance of 9 Quantitative Fecal Immunochemical Tests for Colorectal Cancer Screening Author information Van Solinge WW1, Nielsen FC, Friis-Hansen L, Falkmer UG, Rehfeld JF. Abstract Background To evaluate the hypothesis that gastrin is a local growth factor in colonic carcinomas, the expression of gastrin messenger RNA (mRNA) and […]

Last Posters

3037 / 29 - Progastrin, a novel ubiquitous cancer blood biomarker for early detection and monitoring.

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2294 / 23 - Plasma progastrin level as a predictive and prognostic biomarker in advanced prostate cancer

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2222 / 11 - Progastrin a new biomarker for hepatocellular cancer patient follow-up

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119P - Progastrin, a new blood biomarker for the diagnostic and therapeutic monitoring, in gastro-intestinal cancers: A BIG-RENAPE project.

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